Raising the standard in bioactive protein manufacturing and innovation

Qkine is committed to manufacturing bioactive proteins of the highest quality to enhance scientific outcomes and improve reproducibility.

Our robust animal-free manufacturing platform, along with rigorous quality control procedures, ensures exceptional bioactivity and consistent performance from lot to lot, guaranteeing outstanding performance in your applications. We proactively leverage our expertise in manufacturing and protein engineering to develop unique optimized proteins designed to address fundamental biological, translational and scalability challenges.

Our product portfolio comprises growth factors and cytokines tailored for stem cell and organoid culture, as well as biomarkers and attachment factors. We actively support emerging fields such as cellular agriculture, regenerative medicine, synthetic hydrogels, organ-on-a-chip technology, and bioprinting.

To ensure absolute reproducibility and optimize scientific outcomes, all our products rigorously adhere to the Nine-point Qkine Quality Commitment.

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Scientific areas

Qkine manufacture a portfolio of high purity, highly bioactive growth factors for pluripotent stem cell maintenance and differentiation. Qkine proteins are optimized for research areas such as neural differentiation, organoid culture, cellular agriculture and hematopoietic and hepatic research.

High quality food grade proteins

Qkine food grade growth factors are manufactured under allergen-free HACCP regime with full traceability and documentation.

Thermostable FGF2-G3

Thermostable FGF2-G3 is a hyperstable form of FGF-2 (bFGF), the essential component for the maintenance of pluripotency in stem cell media.

Neural stem cell culture

High-quality growth factors are essential for developing and maintaining robust, reproducible, and physiologically relevant neural cultures.

Products

Qkine proteins are completely animal-origin free and high purity for reproducible cell, stem cell and organoid culture. With bioactivity optimized and guaranteed to be consistent lot-to-lot Qkine growth factors and cytokines are the highest quality, all proteins manufactured in Cambridge, UK

Recombinant human activin A protein (Qk001)

High purity and bioactivity animal origin-free recombinant activin A

  • High-purity bioactive dimer.
  • Extensively validated and benchmarked with other suppliers’ proteins.
  • For reproducible induced pluripotent and embryonic stem cell cultures.
Recombinant human activin A protein (Qk001)

Recombinant human BDNF protein (Qk050)

Animal origin-free high purity BDNF for neuronal stem cell and organoid differentiation and maintenance.

  • Highly bioactive and consistent activity lot-to-lot
  • Extensively tested in neuronal maintenance and differentiation protocols.
  • High purity animal origin-free, carrier-free, tag-free, and non-glycosylated.
Recombinant human BDNF protein (Qk050)

Recombinant human TGF-β1 PLUS™ protein (Qk010)

The first commercially available animal origin-free TGF-β1

  • Bioactive TGF-β1 expressed in E. coli and completely animal origin-free.
  • For highly reproducible results and compatible with chemically-defined stem cell media
  • Used in pluripotent stem cell maintenance media, including E8, StemPro, and mTeSR media.
Recombinant human TGF-β1 PLUS™ protein (Qk010)

Latest News

Explore the latest news on what is happening at Qkine and our blogs with updates on recombinant protein technology, stem cell and organoid research and translational applications.

Pep Talk April 2025

In our March newsletter we celebrate some exciting updates! Our first products in partnership with StemCultures, and more on the way as we collaborate with Tolemy Bio. We also introduce our new differentiation kits, which contain everything you need for iPSC culture and differentiation.

Pep Talk March 2025

In our March newsletter we celebrate some exciting updates! Our first products in partnership with StemCultures, and more on the way as we collaborate with Tolemy Bio. We also introduce our new differentiation kits, which contain everything you need for iPSC culture and differentiation.

Unexpected consequences: growth factor cross-contamination in mammalian and E. coli expressed growth factors

At Qkine we have repeatedly highlighted the need for stricter process and quality control in the manufacture of high purity in recombinant growth factors to prevent cross contamination with related growth factors. Contamination with other bioactive proteins leads to lack of inter and intra-lab reproducibility, or perhaps most concerningly incorrect scientific conclusions.

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Customer Insights

We have used GDF15 from Qkine in cellular experiments and in vivo and it performs very well. Qkine staff are communicative and efficient and delivery times are excellent.

Prof Stephen O'Rahilly

University of Cambridge, UK

Our lab has been using FGF2 and activin A from Qkine in stem cell cultures for many months now. Our epiblast stem cells and trophoblast stem cells never looked better. Qkine has provided us with exceptional customer service and most importantly top-quality, affordable growth factors. We will be definitely using their products in the future.

Prof Jan Zylicz

Novo Nordisk Foundation, University of Copenhagen
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